Refereed Articles and Conference Papers/Presentations/Abstracts

1. Kane, M.D., Springer, J.A., and Sprague, J.E. (2008). Drug Safety Assurance through Clinical Genotyping: Near-Term Considerations for a System-Wide Implementation of Personalized Medicine. Personalized Medicine 5(4): 387-397.
2. Kane, M.D., Springer, J.A., Iannotti, N.V., Gough, E.S., Johns, S.M., Schlueter, S.D. and Sepulve (2008). Identification of Development and Tissue-Specific Gene Expression in the Fathead Minnow Pimephales promelas, Rafinesque using Computational and DNA Microarray Methods. Journal of Fish Biology 72, 2341-2353.
3. Zhang, M., Ouyang, Q., Stephenson, A., Kane, M.D., Salt, D., Prabhakar, S., Burgner, J., Buck, C. (2008). Interactive analysis of systems biology molecular expression data. BMC Systems Bioinformatics 2:23.
4. Kane, M.D. and Summers, K.H. (2007). Challenges and opportunities in pharmacogenomics and therapeutics. Journal of Managed Care Pharmacy 13(7): 607-608.
5. Kane, M.D. and Brewer, J.L. (2007). An Information Technology Emphasis in Biomedical Informatics Education. Journal of Biomedical Informatics 40: 67-72.
6. Kim, H., Kane, M.D., Kim, S., Dominguez, W., Applegate, B.M, and Savikhin, S. A (2007). Molecular Beacon DNA Microarray System for Rapid Detection of E. coli O157:H7 that Eliminates False Signal Risk. Biosensors and Bioelectronics 15:1041-1047.
7. Perry, L., Heard, P., Kane, M., Kim, H., Savikhin, S., Dominguez, W., Applegate, B. (2007). Application of multiplex PCR to the detection of pathogens in food. Journal of Rapid Methods and Automation in Microbiology 15: 176-198.
8. Kemp, M.Q., Liu, W., Thorne, P.A., Kane, M.D., Selmin, O., Romagnolo, D.F. (2006). Induction of the transferrin receptor gene by benzo[a]pyrene in breast cancer MCF-7 cells: Potential as a biomarker of PAH exposure. Environmental and Molecular Mutagenesis 47: 518-526..
9. Kane, M.D. (2005). Technical Issues in DNA Microarray Production and Utilization: Impact on Clinical Research.. Expert Review of Molecular Diagnostics
10. Kane, M.D. (2003). Meeting Highlights: 3rd International Symposium on Early Toxicity Screening: Early ADME-Tox Screening Approaches. Expert Opinion on Drug Safety
11. Nagel, A.C., Thompson, J.D., Marino, M.A., and Kane, M.D (2003). Spanscript: A Novel Method for Deriving Non-Redundant 3’ cDNA Libraries for DNA Microarray Production. Hardiman, G, Microarray Methods and Applications: Nuts and Bolts
12. Kane, M.D., Lin, H-S, Dombkowski, A.A., Diakiw, A., Nagel, A.C., Flexon, A., Leifheit, M., Sprague, (2003). Accelerating Preclinical Drug Development Using A Microarray-Based Method for Detecting Oxidative Enzyme (P450) mRNA Induction and Other Metabolic Genes in the Rat.. Hardiman, G, Microarray Methods and Applications: Nuts & Bolts
13. Kane, M.D. (2002). Aligning experimental design with bioinformatics analysis to meet research objectives.. Cytometry
14. Kane, M.D., Dombkowski, A.A., and Madore, S.J. (2002). The Emerging Utility of Oligonucleotide Microarrays. Lu, Q. and Weiner, M., Gene Cloning and Expression Technologies
15. Kane, M.D. (2001). Screening for xenobiotic-mediated P450 induction using a dedicated DNA microarray protocol.. Journal of Clinical Ligand Assay
16. Sprague, J.E., Worst, T.J., Haynes, K., Mosler, C.R., Nichols, D.E. and Kane, M.D. (2001). The pharmacodynamic characterization of an antisense oligonucleotide against monoamine oxidase-B (MAO-B) in rat brain striatal tissue.. Cellular and Molecular Neurobiology
17. Kane, M.D. and Pisano, M. (2001). Outsourcing genomic and proteomic technology: A value-added solution.. Helix
18. Kane, M.D., Lipinski, W.J., Callahan, M.J., Bian, F., Durham, R.A., Schwarz, R.D. Roher, A.E. and Wa (2000). Evidence for seeding of b-amyloid by intracerebral infusion of Alzheimer brain extracts in b-amyloid precursor protein-transgenic mice. Journal of Neuroscience
19. Kane, M.D., Jatkoe, T.A., Stumpf, C.R., Lu, J., Thomas, J.D, and Madore, S.J. (2000). Assessment of the sensitivity and specificity of oligonucleotide microarrays. Nucleic Acids Research
20. Kane, M.D., Schwarz, R.D., St. Pierre, L., Watson M.D., Emmerling, M.R., Boxer, P.A., and Walker, G. (1999). Inhibitors of V-type ATPases, bafilomycin A1 and concanamycin A, protect against b-amyloid-mediated effects on 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.. Journal of Neurochemistry
21. Kane, M.D., Vanden Heuvel, J.P., Isom, G.E., and Schwarz, R.D. (1998). Differential expression of group I metabotropic glutamate receptors (mGluRs) in PC12 cells: role of nerve growth factor and ras.. Neuroscience Letters
22. Kane, M.D., Yang, C.W., Gunasekar, G. and Isom, G.E. (1998). Trimethyltin stimulates protein kinase C translocation through receptor-mediated phospholipase C activation in PC12 cells.. Journal of Neurochemistry
23. Yan, S.D., Stern, D., Kane, M., Kuo, Y-M., Lampert, H.C., and Roher, A.E. (1998). RAGE-Ab interactions in the pathophysiology of Alzheimer disease.. Restorative Neurology and Neuroscience
24. Pavlakovic, G., Kane, M.D., Eyer, C.L., Kanthasamy, A., and Isom, G.E. (1995). Activation of protein kinase C by trimethyltin: relevance to neurotoxicity.. Journal of Neurochemistry
25. Sun, P., Borowitz, J.L., Kanthasamy, A.G., Kane, M. D., Gunasekar, P.G., and Isom, G.E. (1995). Antagonism of cyanide toxicity by isosorbide dinitrate: possible role of nitric oxide.. Toxicology